Columbus, Ohio, has emerged as a vibrant hub for entrepreneurship, offering a wealth of resources to support local businesses and startups. Whether you’re launching a new venture or scaling an existing one, the city provides numerous programs designed to foster innovation and economic growth.
Rev1 Ventures: Catalyzing Startup Success
Rev1 Ventures stands out as a pivotal player in Columbus’s startup ecosystem. In 2025, Rev1 contributed over $700 million in economic impact to Ohio’s startup scene, demonstrating its commitment to nurturing early-stage companies. Through capital investment, mentorship, and strategic guidance, Rev1 has been instrumental in driving innovation and business growth in the region.
Accelerate Columbus: Comprehensive Business Support
For entrepreneurs seeking structured support, Accelerate Columbus offers tailored programs to meet diverse business needs. The initiative provides two distinct cohorts:
- Grow Your Business: Ensuring Startup Success: Aimed at businesses in the ideation phase or within the first two years of operation, this program focuses on developing comprehensive business plans and financial projections.
- Accelerate 2.0: Beyond the Startup: Designed for businesses operating for three or more years, this cohort delves into growth strategies, including cash flow management, marketing, and cybersecurity.
Both programs leverage the Columbus Chamber of Commerce’s extensive network to provide mentorship, training, and access to capital.
LEAP: Empowering LGBTQ+ Entrepreneurs
Recognizing the need for inclusive entrepreneurial support, the LGBTQ+ Entrepreneurial Accelerator Program (LEAP) focuses on educating and empowering LGBTQ+ community members. LEAP offers education, mentorship, and networking opportunities to help entrepreneurs build confidence and achieve business success.
Ohio State University’s Keenan Center: Academic and Practical Support
The Keenan Center for Entrepreneurship at Ohio State University provides a variety of programs for students, faculty, and external participants. These initiatives aim to build an entrepreneurial community, develop an entrepreneurial mindset, and bring together some of the most innovative minds at Ohio State.
ECDI: Comprehensive Small Business Resources
The Economic and Community Development Institute (ECDI) serves as a one-stop shop for entrepreneurial resources in Ohio. ECDI offers funding, training, mentoring, and more to support small business growth. Their services include small business loans, training programs, and events designed to equip entrepreneurs with the tools needed for success.
Columbus Urban League’s IncubateHer: Supporting Women Entrepreneurs
IncubateHer, an initiative of the Columbus Urban League, is a free incubation program for early-stage entrepreneurs or those in the growth phase of existing businesses. Participants receive tailored growth curricula, peer-to-peer mentoring, networking opportunities, and access to industry-specific mentors.
Ohio Small Business Development Center: Personalized Business Advising
The Ohio Small Business Development Center (SBDC) at Columbus State offers integrated services to meet the needs of small business owners and entrepreneurs. Their core services include free, one-on-one business advising, workshops, strategic business planning, market research, and financial projections development.
By leveraging these resources, Columbus entrepreneurs can access the support and guidance necessary to navigate the challenges of business ownership and contribute to the city’s dynamic economic landscape.

