Columbus, Ohio, has emerged as a vibrant hub for entrepreneurship, offering a wealth of resources to support local businesses and startups. This guide highlights key programs and organizations dedicated to fostering innovation and economic growth in the region.
Rev1 Ventures
Rev1 Ventures stands as a cornerstone in Columbus’s startup ecosystem. In 2025, Rev1 contributed over $700 million in economic impact through capital raised, revenue generated, and business exits. This public-private partnership provides startups with essential support, including funding, mentorship, and strategic guidance, demonstrating resilience even in challenging venture capital markets. Read more
Accelerate Columbus
Offered by the Columbus Chamber of Commerce, Accelerate Columbus is a comprehensive initiative designed to foster innovation and growth among local businesses. The program provides resources such as mentoring, networking opportunities, and access to capital, catering to entrepreneurs at various stages of their business journey. Learn more
LEAP – LGBTQ+ Entrepreneurial Accelerator Program
LEAP focuses on educating and empowering members of the LGBTQ+ community to become successful entrepreneurs. Through education, mentorship, and meaningful connections, LEAP aims to build self-esteem and confidence among its participants, addressing the unique challenges faced by LGBTQ+ entrepreneurs. Discover LEAP
Center for Software Innovation at Ohio State University
The Center for Software Innovation partners with Techstars to offer an accelerator program that drives growth by investing in promising software startups. Selected entrepreneurs receive intensive training, mentorship from top experts, and access to extensive networks, helping them define their products and strategies effectively. Explore the program
Economic & Community Development Institute (ECDI)
ECDI serves as a one-stop shop for entrepreneurial resources, offering funding, training, mentoring, and more. Their programs are designed to assist small business owners in overcoming hurdles to access capital and provide ongoing support through various stages of business development. Visit ECDI
IncubateHer by Columbus Urban League
IncubateHer is a free incubation program targeting early-stage entrepreneurs or those in the growth phase of existing businesses. Participants receive tailored growth curricula, peer-to-peer mentoring, networking opportunities, and access to industry-specific mentors, all aimed at fostering business success. Learn about IncubateHer
JobsOhio Small Business Grants
In 2025, JobsOhio’s Small Business Grant program supported entrepreneurs across the Columbus Region, helping local companies invest in growth and create new jobs. These grants provide targeted funding at pivotal moments, enabling capital purchases, operational expansion, and workforce growth. Read more
By leveraging these resources, Columbus entrepreneurs can access the support and guidance necessary to navigate the challenges of business ownership, contributing to the city’s dynamic and growing economy.